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KMID : 1094020070240020244
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Journal of Veterinary Clinics
2007 Volume.24 No. 2 p.244 ~ p.246
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Idiopathic Polymyositis in a Young Mature Alaskan malamute
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Lee Jae-Il
Hong Sung-Hyeok
Son Hwa-Young
Kim Myung-Cheol
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Abstract
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Clinical and histopathologic features of idopathic polymyositis in twenty-month-old Alaskan malamute dog are described. The clinical signs were progressive exercise intolerance with acute exacerbation of weakness, muscle atrophy, synchronous pelvic limb gait, short stiff steps and tip-toeing as like walking on eggshells. Physical and clinical examination revealed no evidence of neurologic, skeletal and secondary muscular disorders associated with other diseases. Therefore muscle biopsy was performed at the most severe muscle atrophy lesions to confirm by histopathology. Histopathologic findings documented mononuclear cell infiltration and necrosis of muscle fiber and it was diagnosed as idiopathic polymyositis. Initial treatment was focused on pain relief. Prednisone at immunosuppressive dose (2 mg/kg) was administered orally twice daily. After 3 weeks of starting treatment, the patient showed improvement of gait, appetite, exercise as well as gradually return to normal state of hematologic and serum chemistry profiles.
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KEYWORD
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idiopathic, polymyositis, stiff, immunosuppression, Alaskan malamute
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